7-Cyclopentyl-N,N-dimethyl-2-[[5-(1-piperazinyl)-2-pyridinyl]amino]-7H-pyrrolo[2,3-d]pyrimidine-6-carboxamide; LEE 011A; Ribociclib
CAS號(hào):
1211441-98-3
分子式:
C??H??N?O
外觀:
Beige Solid
熔點(diǎn):
>180°C (dec.)
分子量:
434.54
儲(chǔ)存:
-20°C Freezer
溶解度:
DMSO (Slightly), Methanol (Slightly)
種類:
Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
應(yīng)用:
LEE 011 can be used in biological study of kinome-wide RNA interference screen reveals a role for PDK1 in acquired resistance to CDK4/6 inhibition in ER-positive breast cancer.
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