Benzyl 2-Hydroxy-5-nitrobenzoate is a reactant used in the preparation of 4-({[(1S)-(aminocarbonyl)-3-methylbutyl]amino}carbonyl)-2'-({[4-(aminomethyl)phenyl]amino}carbonyl)-4'-(methylamino)biphenyl-2-carboxylic acid, the novel selective and orally available non-amidine TF/FVIIa complex inhibitor.