產(chǎn)品基本信息
產(chǎn)品編號(hào)：B382030
產(chǎn)品名稱：(1R,4S)-(R)-Bicalutamide Sulfide Camphanic Acid Ester
產(chǎn)品CAS：113299-39-1
規(guī)格含量：500mg
產(chǎn)品價(jià)格：面議
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產(chǎn)品詳細(xì)介紹
標(biāo)準(zhǔn)品編號(hào):
B382030
名稱:
(1R,4S)-(R)-Bicalutamide Sulfide Camphanic Acid Ester
別名:
[1R-[1α(R*),4β]]-4,7,7-Trimethyl-3-oxo-1-[[[4-cyano-3-(trifluoromethyl)phenyl]amino]carbonyl]-2-[(4-fluorophenyl)thio]-1-methylethyl Ester 2-Oxabicyclo[2.2.1]heptane-1-carboxylic Acid; (1R,4S)-(R)-1-((4-Cyano-3-(trifluoromethyl)phenyl)amino)-3-((4-fluorophenyl)thio)-2-methyl-1-oxopropan-2-yl 4,7,7-trimethyl-3-oxo-2-oxabicyclo[2.2.1]heptane-1-carboxylate
CAS號(hào):
113299-39-1
分子式:
C??H??F?N?O?S
分子量:
578.58
類別:
Building Blocks; Miscellaneous;
應(yīng)用:
(1R,4S)-(R)-Bicalutamide Sulfide Camphanic Acid Ester is an intermediate in the synthesis of (R)-Bicalutamide (B382005), the (R)-enantiomer of Bicalutamide. Used as an antiandrogen, antineoplastic (hormonal).
文獻(xiàn)
Tucker, H., et al.: J. Med. Chem., 31, 954 (1988); Cockshott, I.D., et al.: Eur. Urol., 18, Suppl. 3, 10 (1990); Cockshott, I., et al.: Br. J. Clin. Pharm., 36, 339 (1993); McKillop, D., et al.: Xenobiotica, 25, 623 (1995)
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