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產(chǎn)品基本信息
產(chǎn)品編號(hào):G407002
產(chǎn)品名稱:Gleevec-d8 Mesylate (Imatinib-d8 Mesylate)
產(chǎn)品CAS:1092942-83-0
規(guī)格含量:5mg
產(chǎn)品價(jià)格:面議
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產(chǎn)品詳細(xì)介紹
標(biāo)準(zhǔn)品編號(hào):
G407002
名稱:
Gleevec-d8 Mesylate (Imatinib-d8 Mesylate)
別名:
4-[(4-Methyl-1-piperazinyl-d8)methyl]-N-[4-methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]phenyl]benzamide Methanesulfonate; CGP 57148B-d8; Gleevac-d8; Glivec-d8; Imatinib-d8 Mesilate; Imatinib-d8 Mesylate; STI 571-d8;
CAS號(hào):
1092942-83-0
參考CAS號(hào):
220127-57-1 unlabelled
分子式:
C??H??D?N?O?S
外觀:
Pale Beige to Yellow Solid
熔點(diǎn):
>109°C (dec.)
分子量:
597.76
儲(chǔ)存:
Hygroscopic, -20°C Freezer, Under Inert Atmosphere
溶解度:
Chloroform (Slightly, Heated), DMSO (Slightly), Methanol (Slightly)
種類:
Standards; Isotopic Labeled Analogues; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
應(yīng)用:
A deuterated tyrosine kinase inhibitor. Highly specific for BCR-ABL, the enzyme associated with chronic myelogenous leukemia (CML) and certain forms of acute lymphoblastic leukemia (ALL).
參考文獻(xiàn)
Schindler, T., et al.: Science, 289, 1938 (2000), Drucker, B.J., et al.: N. Engl. J. Med., 344, 1031 (2001),
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