產(chǎn)品基本信息
產(chǎn)品編號(hào)：H998000
產(chǎn)品名稱(chēng)：Hymenialdisine Methanoate
產(chǎn)品CAS：
規(guī)格含量：2mg
產(chǎn)品價(jià)格：面議
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產(chǎn)品詳細(xì)介紹
標(biāo)準(zhǔn)品編號(hào):
H998000
名稱(chēng):
Hymenialdisine Methanoate
別名:
(4Z)-4-(2-Amino-1,5-dihydro-5-oxo-4H-imidazol-4-ylidene)-2-bromo-4,5,6,7 -tetrahydro-pyrrolo[2,3-c]azepin-8(1H)-one Methanoate; (Z)-Hymenialdisine Methanoate;
參考CAS號(hào):
free base: 82005-12-7; monomethonate 84094-94-0
分子式:
C??H??BrN?O? • x(CH ?O)
外觀:
Pale Yellow to 淡黃色固體
熔點(diǎn):
>245°C (dec.)
分子量:
324.133204
儲(chǔ)存:
-20°C Freezer, Under inert atmosphere
溶解度:
DMSO (Slightly), Methanol (Very Slightly)
種類(lèi):
Standards; Enzyme Activators and Inhibitors;
應(yīng)用:
A potent inhibitor of a variety of kinases including MEK-1, GSK-3Β, and CKI. It also exhibits inhibition of the G2 cell cycle checkpoint at the micromolar concentrations. A marine sponge alkaloid, a natural product.
參考文獻(xiàn)
Cheetham, G., et al.: J. Biol. Chem., 277, 42419 (2002), Bain, J., et al.: Biochem. J., 371, 199 (2003), Sharma, V., et al.: Bioorg. Med. Chem. Lett., 14, 4319 (2004), Anamika, et al.: Proteins, 58, 180 (2005), Birault, V., et al.: Curr. Med. Chem., 13, 1735 (2006),
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