Standards; Pharmaceutical/API Drug Impurities/Metabolites;
應(yīng)用:
Artemisinic O-methanesulfonate is an intermediate used in the synthesis of Amorphadiene (A634365), which is a sesquiterpene synthesized via the cyclization of farnesyl pyrophosphate and a precursor in the biosynthesis ofÂArtemisinin (A777500), which is an effective antimalarial agent used to treat malaria. Genetically modified Saccharomyces cerevisiae can be utilized as an alternative semisynthetic strategy to produce artemisinin from amorphadiene.