產(chǎn)品基本信息
產(chǎn)品編號(hào)：A633385
產(chǎn)品名稱：3-Amino-4-(2,4,5-trifluorophenyl)butanyl Sitagliptin
產(chǎn)品CAS：2072867-07-1
規(guī)格含量：50mg
產(chǎn)品價(jià)格：面議
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產(chǎn)品詳細(xì)介紹
標(biāo)準(zhǔn)品編號(hào):
A633385
名稱:
3-Amino-4-(2,4,5-trifluorophenyl)butanyl Sitagliptin
別名:
(R)-3-Amino-N-((R)-4-oxo-4-(3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)-1-(2,4,5-trifluorophenyl)butan-2-yl)-4-(2,4,5-trifluorophenyl)butanamide
CAS號(hào):
2072867-07-1
分子式:
C??H??F?N?O?
外觀:
白色至白色固體
熔點(diǎn):
>73°C (dec.)
分子量:
622.49
儲(chǔ)存:
冰箱保存
溶解度:
Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
類別:
Standards; Chiral Molecules;
應(yīng)用:
3-Amino-4-(2,4,5-trifluorophenyl)butanyl Sitagliptin is an impurity of Sitagliptin (S490990). Sitagliptin is a trizolopyrazine dipeptidyl peptidase IV inhibitor. It has recently been approved for the therapy of type II diabetes.
文獻(xiàn)
Kim, D., et al.: J. Med. Chem., 48, 141 (2005), Ahren, B., et al.: Eur. J. Pharmacol., 521 164 (2005), Bergman, A., et al: Clin. Ther., 28, 55 (2006)
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