Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
應(yīng)用:
3-(2-Aminoethoxy) Thalidomide SF-1-088 Amide is a potential small molecule inhibitor of Stat3 and Stat5-SH2 domain. Useful in the treatment of human cancers. Antileukemia agent. Derivative of Thalidomide (T338850), Inhibits FGF-induced angiogenesis. Inhibits replication of human immunodeficiency virus type 1. Teratogenic sedative. There is now a growing clinical interest in Thalidomide, and it is introduced as an immunomodulatory agent used primarily in combination with dexamethasone to treat multiple myeloma.