15-Keto Prostaglandin E0-d4 is the isotope labelled analog of 15-Keto Prostaglandin E0 (K202055); a metabolite of Prostaglandin E1 (P838600) that has been shown to induce arterial thromboresistance in experimental animals and in man, but with several magnitudes higher concentrations than Prostaglandin E1. 15-Keto Prostaglandin E0 is also used as the active ingredient in compositions used for the treatment of external secretion disorders.