產(chǎn)品基本信息
產(chǎn)品編號(hào)：D289655
產(chǎn)品名稱：N-Desethyl Sunitinib Hemimalate
產(chǎn)品CAS：1474111-36-8
規(guī)格含量：10mg
產(chǎn)品價(jià)格：面議
聯(lián)系我們:
產(chǎn)品詳細(xì)介紹
標(biāo)準(zhǔn)品編號(hào):
D289655
名稱:
N-Desethyl Sunitinib Hemimalate
別名:
N-[2-(Ethylamino)ethyl]-5-[(Z)-(5-fluoro-1,2-dihydro-2-oxo-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide Hemimalate;
CAS號(hào):
1474111-36-8
參考CAS號(hào):
Free Base: 356068-97-8
分子式:
C??H??FN?O?•1/2C?H?O?
外觀:
Orange Solid
熔點(diǎn):
N/A
分子量:
437.47
儲(chǔ)存:
冰箱保存, under inert atmosphere
溶解性:
DMSO, Methanol
種類:
Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
應(yīng)用:
N-Desethyl Sunitinib Hemimalate is a metabolite of Sunitinib (S820000), a multi-kinase inhibitor targeting several receptor tyrosine kinases (RTK). Antineoplastic.
參考文獻(xiàn)
Sun, L., et al.: J. Med. Chem., 46, 1116 (2003); Mendel, D.B., et al.: Clin. Cancer Res., 9, 327 (2003); Sistla, A., et al.: Drug Dev. Ind. Pharm., 30, 19 (2004); Sakamoto, K.M., et al.: Curr. Opin. Invest. Drugs, 5. 1329 (2004)
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