產(chǎn)品基本信息
產(chǎn)品編號：B692330
產(chǎn)品名稱：(R)-3-((tert-Butoxycarbonyl)amino)-4-(2,4,5-trifluorophenyl)butanoic Acid
產(chǎn)品CAS：486460-00-8
規(guī)格含量：5g
產(chǎn)品價格：面議
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產(chǎn)品詳細介紹
標準品編號:
B692330
名稱:
(R)-3-((tert-Butoxycarbonyl)amino)-4-(2,4,5-trifluorophenyl)butanoic Acid
別名:
(βR)-β-[[(1,1-Dimethylethoxy)carbonyl]amino]-2,4,5-trifluoro-benzenebutanoic Acid; 3R)-3-[(1,1-Dimethylethoxycarbonyl)amino]-4-(2,4,5-trifluorophenyl)butanoic Acid; (3R)-3-[(tert-Butoxycarbonyl)amino]-4-(2,4,5-trifluorophenyl)butanoic Acid; (3R)-3-[N-(tert-Butoxycarbonyl)amino]-4-(2,4,5-trifluorophenyl)butanoic Acid; (R)-3-(((tert-Butoxy)carbonyl)amino)-4-(2,4,5-trifluorophenyl)butyric Acid; (R)-3-[(tert-Butyloxycarbonyl)amino]-4-(2,4,5-trifluorophenyl)butanoic Acid
CAS號:
486460-00-8
分子式:
C??H??F?NO?
外觀:
白色至白色固體
熔點:
129-130°C
分子量:
333.3
儲存:
冰箱保存
溶解度:
Chloroform (Slightly), DMSO (Slightly), Ethyl Acetate (Slightly)
類別:
Research Tools; Pharmaceutical/API Drug Impurities/Metabolites;
應(yīng)用:
(R)-3-((tert-Butoxycarbonyl)amino)-4-(2,4,5-trifluorophenyl)butanoic Acid has been used as a reactant for the preparation of dipeptidyl peptidase-4 (DPP4) inhibitors for the treatment of type 2 diabetes, such as sitagliptin.
參考文獻
Kim, H.J., et. al.: Bioorg. Med. Chem. Lett., 22, 5545 (2012)
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