20(R)-Ginsenoside Rg3-d6 is the labelled version of 20(R)-Ginsenoside Rg3, which causes an inhibition of phosphatidylinositol 3-kinase/Akt activation that, in turn, results in modulations in Bcl-2 family proteins in such a way that the apoptosis of U87 cells are regulated, relating to in vivo inhibition of tumor angiogenesis of lung cancer.