(E)-3-Hydroxydemethylbromhexine is derived from rac-cis-3-Aminocyclohexanol (A603675), which is a compound useful in organic synthesis and 2-Amino-3,5-dibromo-benzaldehyde (A604610), which is a reagent used in the preparation of Ambroxol and Bromhexine (B678600) metabolites Ambroxol EP Impurity E..