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Hydroxy Cyclophosphamide Semicarbazone (80%)

產(chǎn)品基本信息

產(chǎn)品編號(hào)：H926305

產(chǎn)品名稱：Hydroxy Cyclophosphamide Semicarbazone (80%)

產(chǎn)品CAS：53948-46-2

規(guī)格含量：25mg

產(chǎn)品價(jià)格：面議

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產(chǎn)品詳細(xì)介紹

標(biāo)準(zhǔn)品編號(hào):	H926305
名稱:	Hydroxy Cyclophosphamide Semicarbazone (80%)
別名:	N,N-bis(2-chloroethyl)phosphorodiamidic Acid 3-[2-(Aminocarbonyl)hydrazinylidene]propyl Ester; NSC 319519; Aldophosphamide Semicarbazone;
CAS號(hào):	53948-46-2
分子式:	C?H??Cl?N?O?P
外觀:	Colourless to Pale Yellow Oil to Low-Melting Solid
分子量:	334.14
儲(chǔ)存:	Hygroscopic, -20°C Freezer, Under inert atmosphere
溶解度:	Dichloromethane (Sparingly), DMSO (Slightly), Methanol (Slightly)
種類:	Standards; Pharmaceutical/API Drug Impurities/Metabolites;
應(yīng)用:	Aldophosphamide Semicarbazone is a major metabolite of cyclophosphamide (C988580), a cytotoxic nitrogen mustard derivative widely used in cancer chemotherapy. It cross-links DNA, causes strand breakage, and induces mutations. Its clinical activity is associated with a decrease in aldehyde dehydrogenase 1 (ALDH1) activity.This compound is suitable for aldehyde dehydrogenase (ALDH) related research.
參考文獻(xiàn)	Struck, R.F., et al.: Cancer. Rsch., 34, 2933 (1947); Wheeler, A.G., et al.: Toxicol. Appl. Pharmacol., 4, 324 (1962); Fraiser, L.H., et al.: Drugs, 42, 781 (1991); Colvin, O.M., et al.: Curr. Pharmaceut. Design, 5, 555 (1999);

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