產(chǎn)品基本信息
產(chǎn)品編號(hào)：S143753
產(chǎn)品名稱：Saxagliptin Hydrochloride
產(chǎn)品CAS：709031-78-7
規(guī)格含量：100mg
產(chǎn)品價(jià)格：面議
聯(lián)系我們:
產(chǎn)品詳細(xì)介紹
標(biāo)準(zhǔn)品編號(hào):
S143753
名稱:
Saxagliptin Hydrochloride
別名:
(1S,3S,5S)-2-((2S)-2-Amino-2-(3-hydroxyadamantan-1-yl)acetyl)-2-azabicyclo[3.1.0]hexane-3-carbonitrile Hydrochloride;
CAS號(hào):
709031-78-7
參考CAS號(hào):
Free Base: 361442-04-8
分子式:
C??H??N?O? • (HCl)
外觀:
白色固體
熔點(diǎn):
>219°C
分子量:
315.413646
儲(chǔ)存:
-20°C Freezer, Under inert atmosphere
溶解度:
DMSO (Slightly), Methanol (Slightly)
類別:
Standards; Enzyme Activators and Inhibitors;
應(yīng)用:
Saxagliptin is a potent and selective reversible inhibitor of dipeptidyl peptidase-4, which is being developed for the treatment of type 2 diabetes. It is absorbed rapidly after oral administration and has a pharmacokinetic profile compatible with once daily dosing.
參考文獻(xiàn)
Feng, J., et al.: J. Med. Chem., 50, 2297 (2007), Rosenstock, J., et al.: Diabetes Obes. Metab., 10, 376 (2008), Thomas, L., et al.: J. Pharmacol. Exp. Ther., 325, 175 (2008),
?您的位置：
