產(chǎn)品基本信息
產(chǎn)品編號：O870043
產(chǎn)品名稱：1-Oxo Fexofenadine-d10 Methyl Ester
產(chǎn)品CAS：
規(guī)格含量：10mg
產(chǎn)品價(jià)格：面議
聯(lián)系我們:
產(chǎn)品詳細(xì)介紹
標(biāo)準(zhǔn)品編號:
O870043
名稱:
1-Oxo Fexofenadine-d10 Methyl Ester
別名:
4-[4-[4-(Hydroxydiphenyl-d10-methyl)-1-piperidinyl]-1-oxobutyl]-α,α-dimethylbenzeneacetic Acid Methyl Ester; 2-[4-[4-[4-(Hydroxydiphenyl-d10-methyl)-1-piperidinyl]-1-oxobutyl]phenyl]-2,2-dimethylacetic Acid Methyl Ester; Methyl 4-[4-[4-(Hydroxydiphenyl-d10-methyl)-1-piperidinyl]-1-oxobutyl]-α,α-dimethylphenylacetate;
參考CAS號:
Unlabelled: 154477-55-1
分子式:
C??H??D??NO?
分子量:
523.73
類別:
Building Blocks; Isotopic Labeled Analogues;
應(yīng)用:
1-Oxo Fexofenadine-d10 Methyl Ester is the labeled analogue of 1-Oxo Fexofenadine Methyl Ester (O870040), an intermediate in the preparation of Fexofenadine (F322470). It can also be used for the synthesis of an oxidation metabolite of Terfenadine (T114500),a H1-receptor antagonist.
參考文獻(xiàn)
Garteiz, D.A., et al.: Arzneim.-Forsch., 32, 1185 (1982), Rampe, D., et al.: Mol. Pharmacol., 44, 1240 (1993), Obradovic, T., et al.: Pharm. Res., 24, 318 (2007); Kawai, S., et al.: J. Org. Chem., 59, 2620 (1994);
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