 ?您的位置：對(duì)照品 > 試劑耗材 > 生化試劑 > |
|
|
|
| 產(chǎn)品基本信息 |
|
| 產(chǎn)品編號(hào)：127859 |
| 產(chǎn)品名稱：Retaspimycin |
| 產(chǎn)品CAS：857402-23-4 |
| 規(guī)格含量：10MG |
| 產(chǎn)品價(jià)格：5600 |
| 聯(lián)系我們: |
 |
|
 |
|
|
| 產(chǎn)品詳細(xì)介紹 |
Retaspimycin
Product Name： Retaspimycin
CAS號(hào):857402-23-4
分子式:C31H45N3O8
分子量:587.7
貯存： 儲(chǔ)存溫度-20°C
可溶性： DMSO
生化和生理學(xué)機(jī)理：
retaspimycin hydrochloride is the hydrochloride salt of a small-molecule inhibitor of heat shock protein 90 (HSP90) with antiproliferative and antineoplastic activities. Retaspimycin binds to and inhibits the cytosolic chaperone functions of HSP90, which maintains the stability and functional shape of many oncogenic signaling proteins and may be overexpressed or overactive in tumor cells. Retaspimycin-mediated inhibition of HSP90 promotes the proteasomal degradation of oncogenic signaling proteins in susceptible tumor cell populations, which may result in the induction of apoptosis.
|
|
|
|
|
